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Physik-Institut Group of Jan Unkelbach

Research

We focus on 3 areas of research:

  1. Radiotherapy treatment planning: We conduct research on mathematical optimization methods for radiotherapy planning to further improve treatment planning systems. This includes both X-ray therapy and proton therapy, and the combination of protons and X-rays.
  2. Target delineation and outcome prediction: Here, we focus on quantitative analysis of medical images such as MRI, CT and PET, with the goal of precisely defining the region to be irradiated and predicting the patient's response to treatment. Work in this domain is integrated into the UZH Clinical Research Priority Program  Artificial intelligence in oncological imaging
  3. Radiotherapy technology: We work on the development and clinical translation of state-of-the-art radiotherapy technology. Our department is the first in Switzerland to install a MRI-Linac, a combination of MRI scanner and radiotherapy device. In addition, we recently converted a clinically decommissioned linac to 16 MeV electron-FLASH modality. The achievable average dose rates up to 800 Gy/s will be employed to investigate novel detectors and the flash sparing effect in (pre)clinical studies.

A selection of ongoing research projects is described below. Feel free to get in touch if you have questions.

 

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