Publications

ZORA Publication List

Publications

2024

• 2024

  • Journal Article

    • Lynch, Jennifer; Troadec, Estelle; Fung, Tsz Kan; Gladysz, Kornelia; Virely, Clemence; Lau, Priscilla Nga Ieng; Cheung, Ngai; Zeisig, Bernd; Wong, Jason Wing Hon; Lopes, Massimo; Huang, Suming; So, Chi Wai Eric (2024). Hematopoietic stem cell quiescence and DNA replication dynamics maintained by the resilient β-catenin/Hoxa9/Prmt1 axis. Blood:Epub ahead of print.
    • González-Acosta, Daniel; Lopes, Massimo (2024). DNA replication and replication stress response in the context of nuclear architecture. Chromosoma, 133(1):57-75.
2023

• 2023

  • Journal Article

    • Chanou, Anna; Weiβ, Matthias; Holler, Karoline; Sajid, Atiqa; Straub, Tobias; Krietsch, Jana; Sanchi, Andrea; Ummethum, Henning; Lee, Clare S K; Kruse, Elisabeth; Trauner, Manuel; Werner, Marcel; Lalonde, Maxime; Lopes, Massimo; Scialdone, Antonio; Hamperl, Stephan (2023). Single molecule MATAC-seq reveals key determinants of DNA replication origin efficiency. Nucleic Acids Research, 51(22):12303-12324.
    • Palumbieri, Maria Dilia; Merigliano, Chiara; González-Acosta, Daniel; Kuster, Danina; Krietsch, Jana; Stoy, Henriette; von Känel, Thomas; Ulferts, Svenja; Welter, Bettina; Frey, Joël; Doerdelmann, Cyril; Sanchi, Andrea; Grosse, Robert; Chiolo, Irene; Lopes, Massimo (2023). Nuclear actin polymerization rapidly mediates replication fork remodeling upon stress by limiting PrimPol activity. Nature Communications, 14(1):7819.
    • Wildschut, Mattheus H E; Mena, Julien; Dördelmann, Cyril; van Oostrum, Marc; Hale, Benjamin D; Settelmeier, Jens; Festl, Yasmin; Lysenko, Veronika; Schürch, Patrick M; Ring, Alexander; Severin, Yannik; Bader, Michael S; Pedrioli, Patrick G A; Goetze, Sandra; van Drogen, Audrey; Balabanov, Stefan; Skoda, Radek C; Lopes, Massimo; Wollscheid, Bernd; Theocharides, Alexandre P A; Snijder, Berend (2023). Proteogenetic drug response profiling elucidates targetable vulnerabilities of myelofibrosis. Nature Communications, 14(1):6414.
    • Clerbaux, Laure-Alix; Cordier, Pierre; Desboeufs, Nina; Unger, Kristian; Leary, Peter; Semere, Gabriel; Boege, Yannick; Chan, Lap Kwan; Desdouets, Chantal; Lopes, Massimo; Weber, Achim (2023). Mcl-1 deficiency in murine livers leads to nuclear polyploidisation and mitotic errors: Implications for hepatocellular carcinoma. JHEP Reports, 5(10):100838.
    • Rastokina, Anastasia; Cebrián, Jorge; Mozafari, Negin; Mandel, Nicholas H; Smith, C I Edvard; Lopes, Massimo; Zain, Rula; Mirkin, Sergei M (2023). Large-scale expansions of Friedreich's ataxia GAA•TTC repeats in an experimental human system: role of DNA replication and prevention by LNA-DNA oligonucleotides and PNA oligomers. Nucleic Acids Research, 51(16):8532-8549.
    • Andrs, Martin; Stoy, Henriette; Boleslavska, Barbora; Chappidi, Nagaraja; Kanagaraj, Radhakrishnan; Nascakova, Zuzana; Menon, Shruti; Rao, Satyajeet; Oravetzova, Anna; Dobrovolna, Jana; Surendranath, Kalpana; Lopes, Massimo; Janscak, Pavel (2023). Excessive reactive oxygen species induce transcription-dependent replication stress. Nature Communications, 14(1):1791.
    • Stoy, Henriette; Zwicky, Katharina; Kuster, Danina; Lang, Kevin S; Krietsch, Jana; Crossley, Magdalena P; Schmid, Jonas A; Cimprich, Karlene A; Merrikh, Houra; Lopes, Massimo (2023). Direct visualization of transcription-replication conflicts reveals post-replicative DNA:RNA hybrids. Nature Structural & Molecular Biology, 30(3):348-359.
2022

• 2022

  • Journal Article

    • Jacobs, Kurt; Doerdelmann, Cyril; Krietsch, Jana; González-Acosta, Daniel; Mathis, Nicolas; Kushinsky, Saul; Guarino, Estrella; Gómez-Escolar, Carmen; Martinez, Dolores; Schmid, Jonas A; Leary, Peter J; Freire, Raimundo; Ramiro, Almudena R; Eischen, Christine M; Mendez, Juan; Lopes, Massimo (2022). Stress-triggered hematopoietic stem cell proliferation relies on PrimPol-mediated repriming. Molecular Cell, 82(21):4176-4188.e8.
    • Dibitetto, Diego; Marshall, Shannon; Sanchi, Andrea; Liptay, Martin; Badar, Jumana; Lopes, Massimo; Rottenberg, Sven; Smolka, Marcus B (2022). DNA-PKcs promotes fork reversal and chemoresistance. Molecular Cell, 82(20):3932-3942.e6.
    • Giansanti, Celeste; Manzini, Valentina; Dickmanns, Antje; Dickmanns, Achim; Palumbieri, Maria Dilia; Sanchi, Andrea; Kienle, Simon Maria; Rieth, Sonja; Scheffner, Martin; Lopes, Massimo; Dobbelstein, Matthias (2022). MDM2 binds and ubiquitinates PARP1 to enhance DNA replication fork progression. Cell Reports, 39(9):110879.

  • Book Section

    • Stoy, Henriette; Lang, Kevin S; Merrikh, Houra; Lopes, Massimo (2022). Locus-Specific Analysis of Replication Dynamics and Detection of DNA-RNA Hybrids by Immuno Electron Microscopy. In: Aguilera, Andrés; Ruzov, Alexey. R-Loops: Methods and Protocols. New York: Springer, 67-89.
    • Stoy, Henriette; Luethi, Joel; Roessler, Fabienne K; Riemann, Johannes; Kaech, Andres; Lopes, Massimo (2022). Direct R-Loop Visualization on Genomic DNA by Native Automated Electron Microscopy. In: Aguilera, Andrés; Ruzov, Alexey. R-Loops: Methods and Protocols. New York: Springer, 1-20.
2021

• 2021

  • Journal Article

    • Tromans-Coia, Callum; Sanchi, Andrea; Moeller, Giuliana K; Timinszky, Gyula; Lopes, Massimo; Ahel, Ivan (2021). TARG1 protects against toxic DNA ADP-ribosylation. Nucleic Acids Research, 49(18):10477-10492.
    • González-Acosta, Daniel; Blanco-Romero, Elena; Ubieto-Capella, Patricia; Mutreja, Karun; Míguez, Samuel; Llanos, Susana; García, Fernando; Muñoz, Javier; Blanco, Luis; Lopes, Massimo; Méndez, Juan (2021). PrimPol-mediated repriming facilitates replication traverse of DNA interstrand crosslinks. EMBO Journal Online, 40(14):e106355.
2020

• 2020

  • Journal Article

    • Berti, Matteo; Cortez, David; Lopes, Massimo (2020). The plasticity of DNA replication forks in response to clinically relevant genotoxic stress. Nature Reviews. Molecular Cell Biology, 21(10):633-651.
    • Rainey, Michael D; Quinlan, Aisling; Cazzaniga, Chiara; Mijic, Sofija; Martella, Oliviano; Krietsch, Jana; Göder, Anja; Lopes, Massimo; Santocanale, Corrado (2020). CDC7 kinase promotes MRE11 fork processing, modulating fork speed and chromosomal breakage. EMBO Reports, 21(8):e48920.
    • Berti, Matteo; Teloni, Federico; Mijic, Sofija; Ursich, Sebastian; Fuchs, Jevgenij; Palumbieri, Maria Dilia; Krietsch, Jana; Schmid, Jonas A; Garcin, Edwige B; Gon, Stéphanie; Modesti, Mauro; Altmeyer, Matthias; Lopes, Massimo (2020). Sequential role of RAD51 paralog complexes in replication fork remodeling and restart. Nature Communications, 11(1):3531.
    • Takizawa, Hitoshi; Fritsch, Kristin; Kovtonyuk, Larisa V; Saito, Yasuyuki; Yakkala, Chakradhar; Jacobs, Kurt; Ahuja, Akshay K; Lopes, Massimo; Hausmann, Annika; Hardt, Wolf-Dietrich; Gomariz, Álvaro; Nombela-Arrieta, César; Manz, Markus G (2020). Pathogen-induced TLR4-TRIF innate immune signaling in hematopoietic stem cells promotes proliferation but reduces competitive fitness. Cell Stem Cell, 27(1):177.
    • Bai, Gongshi; Kermi, Chames; Stoy, Henriette; Schiltz, Carl J; Bacal, Julien; Zaino, Angela M; Hadden, M Kyle; Eichman, Brandt F; Lopes, Massimo; Cimprich, Karlene A (2020). HLTF Promotes Fork Reversal, Limiting Replication Stress Resistance and Preventing Multiple Mechanisms of Unrestrained DNA Synthesis. Molecular Cell, 78(6):1237-1251.e7.
    • Chappidi, Nagaraja; Nascakova, Zuzana; Boleslavska, Barbora; Zellweger, Ralph; Isik, Esin; Andrs, Martin; Menon, Shruti; Dobrovolna, Jana; Balbo Pogliano, Chiara; Matos, Joao; Porro, Antonio; Lopes, Massimo; Janscak, Pavel (2020). Fork Cleavage-Religation Cycle and Active Transcription Mediate Replication Restart after Fork Stalling at Co-transcriptional R-Loops. Molecular Cell, 77(3):528-541.e8.
2019

• 2019

  • Journal Article

    • Gogola, Ewa; Duarte, Alexandra A; de Ruiter, Julian R; Wiegant, Wouter W; Schmid, Jonas A; de Bruijn, Roebi; James, Dominic I; Llobet, Sergi Guerrero; Vis, Daniel J; Annunziato, Stefano; van den Broek, Bram; Barazas, Marco; Kersbergen, Ariena; van de Ven, Marieke; Tarsounas, Madalena; Ogilvie, Donald J; van Vugt, Marcel; Wessels, Lodewyk F A; Bartkova, Jirina; Gromova, Irina; Andújar-Sánchez, Miguel; Bartek, Jiri; Lopes, Massimo; van Attikum, Haico; Borst, Piet; Jonkers, Jos; Rottenberg, Sven (2019). Correction: Selective Loss of PARG Restores PARylation and Counteracts PARP Inhibitor-Mediated Synthetic Lethality. Cancer Cell, 35(6):950-952.
    • Garzón, Javier; Ursich, Sebastian; Lopes, Massimo; Hiraga, Shin-Ichiro; Donaldson, Anne D (2019). Human RIF1-Protein Phosphatase 1 Prevents Degradation and Breakage of Nascent DNA on Replication Stalling. Cell Reports, 27(9):2558-2566.e4.
2018

• 2018

  • Journal Article

    • Mutreja, Karun; Krietsch, Jana; Hess, Jeannine; Ursich, Sebastian; Berti, Matteo; Roessler, Fabienne K; Zellweger, Ralph; Patra, Malay; Gasser, Gilles; Lopes, Massimo (2018). ATR-Mediated Global Fork Slowing and Reversal Assist Fork Traverse and Prevent Chromosomal Breakage at DNA Interstrand Cross-Links. Cell Reports, 24(10):2629-2642.e5.
    • Schmid, Jonas Andreas; Berti, Matteo; Walser, Franziska; Raso, Maria Chiara; Schmid, Fabian; Krietsch, Jana; Stoy, Henriette; Zwicky, Katharina; Ursich, Sebastian; Freire, Raimundo; Lopes, Massimo; Penengo, Lorenza (2018). Histone Ubiquitination by the DNA Damage Response Is Required for Efficient DNA Replication in Unperturbed S Phase. Molecular Cell, 71(6):897-910.e8.
    • Menin, Luca; Ursich, Sebastian; Trovesi, Camilla; Zellweger, Ralph; Lopes, Massimo; Longhese, Maria Pia; Clerici, Michela (2018). Tel1/ATM prevents degradation of replication forks that reverse after topoisomerase poisoning. EMBO Reports:e45535.
    • Hafner, Lukas; Lezaja, Aleksandra; Zhang, Xu; Lemmens, Laure; Shyian, Maksym; Albert, Benjamin; Follonier, Cindy; Nunes, Jose Manuel; Lopes, Massimo; Shore, David; Mattarocci, Stefano (2018). Rif1 Binding and Control of Chromosome-Internal DNA Replication Origins Is Limited by Telomere Sequestration. Cell Reports, 23(4):983-992.

  • Book Section

    • Zellweger, Ralph; Lopes, Massimo (2018). Dynamic Architecture of Eukaryotic DNA Replication Forks In Vivo, Visualized by Electron Microscopy. In: Muzi-Falconi, Marco; Brown, Grant W. Genome Instability : Methods and Protocols. New York: Springer, 261-294.
2017

• 2017

  • Journal Article

    • Mijic, Sofija; Zellweger, Ralph; Chappidi, Nagaraja; Berti, Matteo; Jacobs, Kurt; Mutreja, Karun; Ursich, Sebastian; Ray Chaudhuri, Arnab; Nussenzweig, Andre; Janscak, Pavel; Lopes, Massimo (2017). Replication fork reversal triggers fork degradation in BRCA2-defective cells. Nature Communications, 8:859.
    • Boege, Yannick; Malehmir, Mohsen; Healy, Marc E; Wolf, Monika Julia; Böhm, Friederike; Frick, Lukas; Maire, Renaud; Moch, Holger; Heikenwalder, Mathias; Weber, Achim; Lopes, Massimo; et al (2017). A Dual Role of Caspase-8 in Triggering and Sensing Proliferation-Associated DNA Damage, a Key Determinant of Liver Cancer Development. Cancer Cell, 32(3):342-359.e10.
    • Vujanovic, Marko; Krietsch, Jana; Raso, Maria Chiara; Terraneo, Nastassja; Zellweger, Ralph; Schmid, Jonas A; Taglialatela, Angelo; Huang, Jen-Wei; Holland, Cory L; Zwicky, Katharina; Herrador, Raquel; Jacobs, Heinz; Cortez, David; Ciccia, Alberto; Penengo, Lorenza; Lopes, Massimo (2017). Replication Fork Slowing and Reversal upon DNA Damage Require PCNA Polyubiquitination and ZRANB3 DNA Translocase Activity. Molecular Cell, 67(5):882-890.e5.
    • Takizawa, Hitoshi; Fritsch, Kristin; Kovtonyuk, Larisa V; Saito, Yasuyuki; Yakkala, Chakradhar; Jacobs, Kurt; Ahuja, Akshay K; Lopes, Massimo; Hausmann, Annika; Hardt, Wolf-Dietrich; Gomariz, Álvaro; Nombela-Arrieta, César; Manz, Markus G (2017). Pathogen-induced TLR4-TRIF innate immune signaling in hematopoietic stem cells promotes proliferation but reduces competitive fitness. Cell Stem Cell, 21(2):225-240.e5.
    • Vindigni, Alessandro; Lopes, Massimo (2017). Combining electron microscopy with single molecule DNA fiber approaches to study DNA replication dynamics. Biophysical Chemistry, 225:3-9.
2016

• 2016

  • Journal Article

    • Piwko, Wojciech; Mlejnkova, Lucie J; Mutreja, Karun; Ranjha, Lepakshi; Stafa, Diana; Smirnov, Alexander; Brodersen, Mia M L; Zellweger, Ralph; Sturzenegger, Andreas; Janscak, Pavel; Lopes, Massimo; Peter, Matthias; Cejka, Petr (2016). The MMS22L-TONSL heterodimer directly promotes RAD51-dependent recombination upon replication stress. EMBO Journal Online, 35:2584-2601.
    • Galanos, Panagiotis; Vougas, Konstantinos; Walter, David; Polyzos, Alexander; Maya-Mendoza, Apolinar; Haagensen, Emma J; Kokkalis, Antonis; Roumelioti, Fani-Marlen; Gagos, Sarantis; Tzetis, Maria; Canovas, Begoña; Igea, Ana; Ahuja, Akshay K; Zellweger, Ralph; Havaki, Sofia; Kanavakis, Emanuel; Kletsas, Dimitris; Roninson, Igor B; Garbis, Spiros D; Lopes, Massimo; Nebreda, Angel; Thanos, Dimitris; Blow, J Julian; Townsend, Paul; Sørensen, Claus Storgaard; Bartek, Jiri; Gorgoulis, Vassilis G (2016). Chronic p53-independent p21 expression causes genomic instability by deregulating replication licensing. Nature Cell Biology, 18(7):777-789.
    • Ribeyre, Cyril; Zellweger, Ralph; Chauvin, Maeva; Bec, Nicole; Larroque, Christian; Lopes, Massimo; Constantinou, Angelos (2016). Nascent DNA proteomics reveals a chromatin remodeler required for topoisomerase i loading at replication forks. Cell Reports, 15(2):300-309.
    • Ahuja, Akshay K; Jodkowska, Karolina; Teloni, Federico; Bizard, Anna H; Zellweger, Ralph; Herrador, Raquel; Ortega, Sagrario; Hickson, Ian D; Altmeyer, Matthias; Mendez, Juan; Lopes, Massimo (2016). A short G1 phase imposes constitutive replication stress and fork remodelling in mouse embryonic stem cells. Nature Communications, 7:10660-10671.
2015

• 2015

  • Journal Article

    • Gemble, Simon; Ahuja, Akshay; Buhagiar-Labarchède, Géraldine; Onclercq-Delic, Rosine; Dairou, Julien; Biard, Denis S F; Lambert, Sarah; Lopes, Massimo; Amor-Guéret, Mounira (2015). Pyrimidine Pool Disequilibrium Induced by a Cytidine Deaminase Deficiency Inhibits PARP-1 Activity, Leading to the Under Replication of DNA. PLoS Genetics, 11(7):e1005384.
    • Fugger, Kasper; Mistrik, Martin; Neelsen, Kai J; Yao, Qi; Zellweger, Ralph; Kousholt, Arne Nedergaard; Haahr, Peter; Chu, Wai Kit; Bartek, Jiri; Lopes, Massimo; Hickson, Ian D; Sørensen, Claus Storgaard (2015). FBH1 Catalyzes Regression of Stalled Replication Forks. Cell Reports, 10(10):1749-1757.
    • Zellweger, Ralph; Dalcher, Damian; Mutreja, Karun; Berti, Matteo; Schmid, Jonas A; Herrador, Raquel; Vindigni, Alessandro; Lopes, Massimo (2015). Rad51-mediated replication fork reversal is a global response to genotoxic treatments in human cells. Journal of Cell Biology, 208(5):563-579.
    • Thangavel, Saravanabhavan; Berti, Matteo; Levikova, Maryna; Pinto, Cosimo; Gomathinayagam, Shivasankari; Vujanovic, Marko; Zellweger, Ralph; Moore, Hayley; Lee, Eu Han; Hendrickson, Eric A; Cejka, Petr; Stewart, Sheila; Lopes, Massimo; Vindigni, Alessandro (2015). DNA2 drives processing and restart of reversed replication forks in human cells. Journal of Cell Biology, 208(5):545-562.
    • Neelsen, Kai J; Lopes, Massimo (2015). Replication fork reversal in eukaryotes: from dead end to dynamic response. Nature Reviews. Molecular Cell Biology, 16(4):207-220.
    • Fumasoni, Marco; Zwicky, Katharina; Vanoli, Fabio; Lopes, Massimo; Branzei, Dana (2015). Error-Free DNA Damage Tolerance and Sister Chromatid Proximity during DNA Replication Rely on the Polα/Primase/Ctf4 Complex. Molecular Cell:1-13.
2014

• 2014

  • Journal Article

    • Ray Chaudhuri, Arnab; Ahuja, Akshay Kumar; Herrador, Raquel; Lopes, Massimo (2014). Poly(ADP-ribosyl)gycohydrolase (PARG) prevents the accumulation of unusual replication structures during unperturbed S phase. Molecular and Cellular Biology:1-33.
    • Giannattasio, Michele; Zwicky, Katharina; Follonier, Cindy; Foiani, Marco; Lopes, Massimo; Branzei, Dana (2014). Visualization of recombination-mediated damage bypass by template switching. Nature Structural & Molecular Biology, 21(10):884-892.
    • Mejlvang, Jakob; Feng, Yunpeng; Alabert, Constance; Neelsen, Kai J; Jasencakova, Zuzana; Zhao, Xiaobei; Lees, Michael; Sandelin, Albin; Pasero, Philippe; Lopes, Massimo; Groth, Anja (2014). New histone supply regulates replication fork speed and PCNA unloading. Journal of Cell Biology, 204(1):29-43.

  • Book Section

    • Follonier, Cindy; Lopes, Massimo (2014). Combined bidimensional electrophoresis and electron microscopy to study specific plasmid DNA replication intermediates in human cells. In: Stockert, Juan C; Espada, Jesús; Blázquez-Castro, Alfonso. Functional Analysis of DNA and Chromatin. New York, USA: Humana Press (Springer), 209-219.
    • Neelsen, Kai J; Chaudhuri, Arnab Ray; Follonier, Cindy; Herrador, Raquel; Lopes, Massimo (2014). Visualization and interpretation of eukaryotic DNA replication intermediates in vivo by electron microscopy. In: Stockert, Juan C; Espada, Jesús; Blázquez-Castro, Alfonso. Functional Analysis of DNA and Chromatin. New York, USA: Humana Press (Springer), 177-208.
2013

• 2013

  • Journal Article

    • Neelsen, Kai J; Zanini, Isabella M Y; Mijic, Sofija; Herrador, Raquel; Zellweger, Ralph; Ray Chaudhuri, Arnab; Creavin, Kevin D; Blow, J Julian; Lopes, Massimo (2013). Deregulated origin licensing leads to chromosomal breaks by rereplication of a gapped DNA template. Genes and Development, 27(23):2537-2542.
    • Berti, Matteo; Chaudhuri, Arnab Ray; Thangavel, Saravanabhavan; Gomathinayagam, Shivasankari; Kenig, Sasa; Vujanovic, Marko; Odreman, Federico; Glatter, Timo; Graziano, Simona; Mendoza-Maldonado, Ramiro; Marino, Francesca; Lucic, Bojana; Biasin, Valentina; Gstaiger, Matthias; Aebersold, Ruedi; Sidorova, Julia M; Monnat, Raymond J; Lopes, Massimo; Vindigni, Alessandro (2013). Human RECQ1 promotes restart of replication forks reversed by DNA topoisomerase I inhibition. Nature Structural & Molecular Biology, 20(3):347-354.
    • Follonier, Cindy; Oehler, Judith; Herrador, Raquel; Lopes, Massimo (2013). Friedreich's ataxia-associated GAA repeats induce replication-fork reversal and unusual molecular junctions. Nature Structural & Molecular Biology, 20(4):486-494.
    • Neelsen, Kai J; Zanini, Isabella M Y; Herrador, Raquel; Lopes, Massimo (2013). Oncogenes induce genotoxic stress by mitotic processing of unusual replication intermediates. Journal of Cell Biology, 200(6):699-708.
2012

• 2012

  • Journal Article

    • Peña-Diaz, Javier; Bregenhorn, Stephanie; Ghodgaonkar, Medini; Follonier, Cindy; Artola-Borán, Mariela; Castor, Dennis; Lopes, Massimo; Sartori, Alessandro A; Jiricny, Josef (2012). Noncanonical Mismatch Repair as a Source of Genomic Instability in Human Cells. Molecular Cell, 47(5):669-680.
    • Ray Chaudhuri, Arnab; Hashimoto, Yoshitami; Herrador, Raquel; Neelsen, Kai J; Fachinetti, Daniele; Bermejo, Rodrigo; Cocito, Andrea; Costanzo, Vincenzo; Lopes, Massimo (2012). Topoisomerase I poisoning results in PARP-mediated replication fork reversal. Nature Structural and Molecular Biology, 19(4):417-423.
2011

• 2011

  • Journal Article

    • Toller, I M; Neelsen, K J; Steger, M; Hartung, M L; Hottiger, M O; Stucki, M; Kalali, B; Gerhard, M; Sartori, Alessandro A; Lopes, Massimo; Müller, Anne (2011). Carcinogenic bacterial pathogen Helicobacter pylori triggers DNA double-strand breaks and a DNA damage response in its host cells. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 108(36):14944-14949.
    • Engels, K; Giannattasio, M; Muzi-Falconi, M; Lopes, Massimo; Ferrari, S (2011). 14-3-3 proteins regulate exonuclease 1-dependent processing of stalled replication forks. PLoS Genetics, 7(4):e1001367.
2010

• 2010

  • Journal Article

    • Hashimoto, Y; Chaudhuri, A R; Lopes, Massimo; Costanzo, V (2010). Rad51 protects nascent DNA from Mre11-dependent degradation and promotes continuous DNA synthesis. Nature Structural and Molecular Biology, 17(11):1305-1311.
    • Giannattasio, M; Follonier, C; Tourrière, H; Puddu, F; Lazzaro, F; Pasero, P; Lopes, Massimo; Plevani, P; Muzi-Falconi, M (2010). Exo1 competes with repair synthesis, converts NER intermediates to long ssDNA gaps, and promotes checkpoint activation. Molecular Cell, 40(1):50-62.
2009

• 2009

  • Journal Article

    • Lopes, Massimo (2009). Electron microscopy methods for studying in vivo DNA replication intermediates. Methods in Molecular Biology, 521:605-631.
2007

• 2007

  • Journal Article

    • Mojas, N; Lopes, Massimo; Jiricny, J (2007). Mismatch repair-dependent processing of methylation damage gives rise to persistent single-stranded gaps in newly replicated DNA. Genes and Development, 21(24):3342-55.
2006

• 2006

  • Journal Article

    • Liberi, G; Cotta-Ramusino, C; Lopes, Massimo; Sogo, J; Conti, C; Bensimon, A; Foiani, M (2006). Methods to study replication fork collapse in budding yeast. Methods in Enzymology, 409:442-62.
    • Lopes, Massimo; Foiani, M; Sogo, J M (2006). Multiple mechanisms control chromosome integrity after replication fork uncoupling and restart at irreparable UV lesions. Molecular Cell, 21(1):15-27.
2005

• 2005

  • Journal Article

    • Cotta-Ramusino, C; Fachinetti, D; Lucca, C; Doksani, Y; Lopes, Massimo; Sogo, J; Foiani, M (2005). Exo1 processes stalled replication forks and counteracts fork reversal in checkpoint-defective cells. Molecular Cell, 17(1):153-159.
    • Liberi, G; Maffioletti, G; Lucca, C; Chiolo, I; Baryshnikova, A; Cotta-Ramusino, C; Lopes, Massimo; Pellicioli, A; Harber, J E; Foiani, M (2005). Rad51-dependent DNA structures accumulate at damaged replication forks in sgs1 mutants defective in the yeast ortholog of BLM RecQ helicase. Genes and Development, 19(3):339-350.
2004

• 2004

  • Journal Article

    • Grossi, S; Puglisi, A; Dmitriev, P V; Lopes, Massimo; Shore, D (2004). Pol12, the B subunit of DNA polymerase alpha, functions in both telomere capping and length regulation. Genes and Development, 18(9):992-1006.
2003

• 2003

  • Journal Article

    • Lopes, Massimo; Cotta-Ramusino, C; Liberi, G; Foiani, M (2003). Branch migrating sister chromatid junctions form at replication origins through Rad51/Rad52-independent mechanisms. Molecular Cell, 12(6):1499-1510.
2002

• 2002

  • Journal Article

    • Sogo, J M; Lopes, Massimo; Foiani, M (2002). Fork reversal and ssDNA accumulation at stalled replication forks owing to checkpoint defects. Science, 297(5581):599-602.